Personal Injury Law

 

Office Locations

Tallahassee
(Map and Directions)
3375-A Capital Circle N.E.
Tallahassee, FL 32308
Toll Free Phone: (877) ALL WE DO
Local Phone: (850) 553-HELP
or (850) 422-7773
Fax: (850) 422-3449

Thomasville
(Map and Directions)
214 West Jackson Street
Thomasville, GA 31792
Toll Free Phone: (877) ALL WE DO
Local Phone: (229) 226-HELP
(229) 226-4357

 

Video Messages

Safety Problems Associated with
Cholesterol-lowering Drug Crestor

Rosuvastatin (CRESTOR) became the sixth cholesterol lowering "statin" drug on the U.S. market when it was approved by the Food and Drug Administration (FDA) on August 13, 2003. The other members of the statin family are atorvastatin (LIPITOR), fluvastatin (LESCOL), lovastatin (MEVACOR), pravastatin (PRAVACHOL), and simvastatin (ZOCOR). These drugs are only approved to be used along with a low-cholesterol diet and an exercise program to lower cholesterol.

Of the approved statins, cerivastatin (BAYCOL), was removed from the market because of at least 31 reports of fatal rhabdomyolysis, an adverse reaction involving the destruction of muscle tissue that can lead to kidney failure.

AstraZeneca originally filed its application with the FDA to market rosuvastatin in June 2001. The application was delayed when the company halted clinical trials worldwide. After reports of kidney damage and muscle weakness (an early signal for rhabdomyolysis) in clinical trials in patients taking 80 milligrams of the drug per day, the FDA asked AstraZeneca for more data. The company stopped development of the 80 milligram dose because of the safety problems, and rosuvastatin will only be sold in 5, 10, 20, and 40 milligram strengths.

On July 9, 2003, Public Citizen petitioned the FDA to withhold approval of rosuvastatin because of its unique potential to cause kidney toxicity. In the FDA review documents posted on the agency's website before the Endocrinologic and Metabolic Drugs Advisory Committee it was noted "In contrast to currently approved statins, rosuvastatin was also associated with renal [kidney] findings not previously reported with other statins."

If you or a loved one believe that they have been harmed by Crestor, we can help. When it comes to dangerous drugs, Fonvielle Lewis Messer & McConnaughhay represents clients throughout the United States. We can assist you wherever you live. For more information, please call us at (800) 876-7773.

 

  • Fonvielle Lewis Messer & McConnaughhay  •  3375 Capital Circle NE, Tallahassee, Florida 32308   •  (850) 422–7773  •  Contact Us